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Mean platelet volume and red cell distribution width as potential new biomarkers in children with gastroesophageal reflux disease 

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Mean platelet volume and red cell distribution width as potential new biomarkers in children with gastroesophageal reflux disease 

Mean platelet volume and red cell distribution width as potential new biomarkers in children with gastroesophageal reflux disease       [HTML] from nih.gov

Authors

Nurhayat Ozkan Sevencan, Ozkan Cesur, Murat Cakar, Erkan Dogan, Aysegul Ertinmaz Ozkan, Ali Ramazan Benli

Publication date

2019

Journal

American Journal of Translational Research

Volume

11

Issue

5

Pages

3176

Publisher

e-Century Publishing Corporation

Description

The aim of this study was to calculate the corrected rate of reflux in children with gastroesophageal reflux (GER)-like complaints by 24-hour pH monitoring and esophagogastroduodenoscopy (EGD), and to determine the utility of mean platelet volume (MPV) and red cell distribution width (RDW) as diagnostic biomarkers of GER disease (GERD) in children. The subjects in this prospective study were 109 children, 6 to 18 years old. Of them, 74 subjects were with GER symptoms and 35 healthy controls. The subjects were divided into three groups: those who underwent 24-hour pH monitoring (Group 1), those who underwent EGD together with pH monitoring (Group 2), and the healthy controls (Group 3). The results of pH monitoring and EGD and hematological parameters with controls were compared between Groups 1 and 2. In Groups 1 and 2, the overall rate of reflux was 40%, of esophagitis was 27.8%, and of …

Scholar articles

Mean platelet volume and red cell distribution width as potential new biomarkers in children with gastroesophageal reflux disease

NO Sevencan, O Cesur, M Cakar, E Dogan, AE Ozkan… - American Journal of Translational Research, 2019

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